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Acute lung injury in acute pancreatitis - Awaiting the big leap.

Author

Summary, in English

Acute lung injury is a severe complication to acute pancreatitis and a significant health problem associated with a considerable mortality. Underlying mechanisms are complex and poorly understood, although recent insights have identified several inflammatory profiles and cellular components involved to varying degrees during different phases of pancreatitis exacerbation and acute lung injury. This review aims to highlight the current understanding of the inflammatory and cellular components involved in and responsible for the associations of acute pancreatitis and acute lung injury, with the hope of thereby providing an increased understanding of the underlying mechanisms. In addition, novel experimental models of modulating the pancreatitis-associated acute lung injury are presented, interventions that may be of potential future clinical value.

Publishing year

2012

Language

English

Pages

1199-1210

Publication/Series

Respiratory Medicine

Volume

106

Issue

9

Document type

Journal article review

Publisher

Elsevier

Topic

  • Respiratory Medicine and Allergy

Status

Published

Research group

  • Lung Biology

ISBN/ISSN/Other

  • ISSN: 1532-3064