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Oxaspirodion, a new inhibitor of inducible TNF-alpha expression from the ascomycete Chaetomium subspirale

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Author

Summary, in English

In a search for new inhibitors of the TNF-alpha promoter activity, a new spiro-compound, designated oxaspirodion, was obtained as a mixture of four isomers from fermentations of the ascomycete Chaetomium subspirale. The structure was determined by a combination of spectroscopic techniques.

Publishing year

2004

Language

English

Pages

493-495

Publication/Series

Journal of Antibiotics

Volume

57

Issue

8

Document type

Journal article

Publisher

Japan Antibiotics Research Association

Topic

  • Organic Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 0021-8820