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Human blood groups: inheritance and importance in transfusion medicine

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Author

Summary, in English

Human blood group antigens are unique, inherited polymorphisms on the extracellular surface of red blood cells. They have been used as genetically discrete markers of human polymorphism since the discovery of the ABO system in 1900. Since then, many blood group antigens have been identified, the genes cloned, and their biological significance elucidated. Blood group antigens and antibodies play an important role in Transfusion Medicine. In addition, blood groups have provided anthropologists with a tool to study polymorphism in the different peoples across the world and provided geneticists with inherited markers to understand complex mechanisms of linkage and disease inheritance.

Publishing year

2003

Language

English

Pages

367-372

Publication/Series

Journal of Infusion Nursing

Volume

26

Issue

6

Document type

Journal article

Publisher

Lippincott Williams & Wilkins

Topic

  • Hematology

Status

Published

ISBN/ISSN/Other

  • ISSN: 1533-1458