Specific conditions for enhancement of lipoprotein lipase activity by platelets

Summary, in English

Homogenates of human blood platelets, but not of red blood cells, have been found to stimulate lipoprotein lipase activity only when assayed against an emulsified triglyceride substrate sonicated for a short period of time. The degree of stimulation was inversely related to the time of sonication of the substrate. Using chylomicrons as substrate no stimulation of lipoprotein lipase activity by platelet homogenate was seen.

• Author: Peter Nilsson-Ehle; Arlene S Garfinkel; Michael C Schotz
• Department/s: Division of Clinical Chemistry and Pharmacology
• Publishing year: 1975
• Language: English
• Pages: 1703-1709
• Publication/Series: Life Sciences
• Volume: 16
• Issue: 11
• Links: http://dx.doi.org/10.1016/0024-3205(75)90054-5
• Document type: Journal article
• Publisher: Elsevier
• Topic: Pharmacology and Toxicology; Medicinal Chemistry
• Status: Published
• ISBN/ISSN/Other: ISSN: 1879-0631