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Biopsy sampling requirements for the estimation of muscle capillarization

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Author

Summary, in English

The aim of this study was to determine the number of tibialis anterior biopsy samples and muscle fibers required to estimate the capillary supply of individual muscle fibers (C:F-i). C:F-i was calculated for 25 type 1 fibers in each of 8 images from 3 biopsies of 5 young healthy individuals. Sequential estimation analysis indicated that 50 fibers from one biopsy are sufficient to characterize the C:F-i of the tibialis anterior for a group of subjects. Thus, when analyzing the capillarization of the tibialis anterior, the requirements of only one biopsy sample and 50 fibers means a great reduction in time for analysis and in the invasiveness of the procedure. (C) 2002 Wiley Periodicals, Inc.

Department/s

Publishing year

2002

Language

English

Pages

546-548

Publication/Series

Muscle and Nerve

Volume

26

Issue

4

Document type

Journal article

Publisher

John Wiley & Sons Inc.

Topic

  • Other Clinical Medicine

Keywords

  • biopsy methods
  • capillaries
  • skeletal
  • muscle

Status

Published

ISBN/ISSN/Other

  • ISSN: 0148-639X