Suzuki reaction catalysed by a PCsp3P pincer Pd(II) complex: Evidence for a mechanism involving molecular species
Author
Summary, in English
{Cis-1,3-bis[(di-tert-butylphosphino)methyl]cyclohexyl}palladium(II)trif luoroacetate (1) acts as a precatalyst for the Suzuki reaction of aryl halides with phenylboronic acid in the absence or presence of mercury to give the product in modest to reasonably good yields. The reaction was monitored by P-31- and H-1 NMR spectroscopy in a stepwise fashion, concluding that complex 1 reacts with activated boronic acids in the first reaction step to yield the corresponding phenyl complex 2. Complex 2 thereafter generates the Suzuki cross-coupling product upon addition of aryl halide. This shows that (PCP)Pd complexes, in addition to the previously demonstrated Pd(0)/Pd(II) mechanism, can mediate cross-coupling reactions using molecular species in a non-zero oxidation state. (C) 2009 Elsevier B.V. All rights reserved.
Department/s
Publishing year
2009
Language
English
Pages
3112-3115
Publication/Series
Journal of Organometallic Chemistry
Volume
694
Issue
19
Links
Document type
Journal article
Publisher
Elsevier
Topic
- Organic Chemistry
Keywords
- Pincer ligands
- Palladium
- Cross-coupling
- NMR studies
Status
Published
ISBN/ISSN/Other
- ISSN: 0022-328X