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Platelet secretion of CXCL4 is Rac1-dependent and regulates neutrophil infiltration and tissue damage in septic lung damage.

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Author

Summary, in English

Platelets are potent regulators of neutrophil accumulation in septic lung damage. We hypothesized that platelet-derived CXCL4 might support pulmonary neutrophilia in a murine model of abdominal sepsis.

Publishing year

2015

Language

English

Pages

5347-5359

Publication/Series

British Journal of Pharmacology

Volume

172

Issue

22

Document type

Journal article

Publisher

Wiley

Topic

  • Immunology in the medical area
  • Anesthesiology and Intensive Care

Status

Published

Research group

  • Surgery
  • Diabetes - Islet Patophysiology

ISBN/ISSN/Other

  • ISSN: 1476-5381