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High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.

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Author

Summary, in English

The majority of acute coronary syndromes are caused by plaque ruptures. Proteases secreted by macrophages play an important role in plaque ruptures by degrading extracellular matrix proteins in the fibrous cap. Matrix metalloproteinases have been shown to be markers for cardiovascular disease whereas the members of the cathepsin protease family are less studied.

Publishing year

2016

Language

English

Pages

000353-000353

Publication/Series

Open Heart

Volume

3

Issue

1

Document type

Journal article

Publisher

BMJ Publishing Group

Topic

  • Cardiac and Cardiovascular Systems

Status

Published

Research group

  • Cardiovascular Research - Translational Studies
  • Cardiovascular Research - Immunity and Atherosclerosis
  • Cardiovascular Research - Epidemiology

ISBN/ISSN/Other

  • ISSN: 2053-3624