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The Malmö Diet and Cancer Study: representativity, cancer incidence and mortality in participants and non-participants

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Author

Summary, in English

In order to investigate potential selection bias in population-based cohort studies, participants (n = 28098) and non-participants (n = 40807) in the Malmo Diet and Cancer Study (MDCS) were compared with regard to cancer incidence and mortality. MDCS participants were also compared with participants in a mailed health survey with regard to subjective health, socio-demographic characteristics and lifestyle. Cancer incidence prior to recruitment was lower in non-participants, Cox proportional hazards analysis yielded a relative risk (RR) with a 95% confidence interval of 0.95 (0.90-1.00), compared with participants. During recruitment, cancer incidence was higher in non-participants, RR: 1.08 (1.01-1.17). Mortality was higher in non-participants both during, 3.55 (3.13-4.03), and following the recruitment period, 2.21 (2.03-2.41). The proportion reporting good health was higher in the MDCS than in the mailed health survey (where 74.6% participated), but the socio-demographic structure was similar. We conclude that mortality is higher in non-participants than in participants during recruitment and follow-up. It is also suggested that non-participants may have a lower cancer incidence prior to recruitment but a higher incidence during the recruitment period.

Publishing year

2001

Language

English

Pages

489-499

Publication/Series

European Journal of Cancer Prevention

Volume

10

Issue

6

Document type

Journal article

Publisher

Lippincott Williams & Wilkins

Topic

  • Cancer and Oncology

Keywords

  • socio-demography
  • representativity
  • participants
  • non-participants
  • Cancer incidence
  • mortality

Status

Published

Research group

  • Surgery
  • Geriatric Medicine
  • Nutrition Epidemiology
  • Cardiovascular Research - Epidemiology
  • Social Medicine and Health Policy
  • Internal Medicine - Epidemiology

ISBN/ISSN/Other

  • ISSN: 1473-5709