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Steroid hormone determination in water using an environmentally friendly membrane based extraction technique.

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Author

  • Saioa Zorita
  • Pär Hallgren
  • Lennart Mathiasson

Summary, in English

In this study, a method was developed for determination of steroid hormones (17beta-estradiol, estrone, 17alpha-ethynylestradiol) in tap and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up combined with gas chromatography-mass spectrometry (GC-MS). In this approach, only the organic liquid in the lumen (10muL) of the hollow-fibre membrane was utilised for depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, salt and humic acid content. The optimised method allowed the determination of the analyte at the low ngL(-1) level in tap and sewage water. A linear plot gave correlation coefficients better than 0.995 and resulted in a method limit of detection of 1.6, 3 and 10ngL(-1) for 17beta-estradiol, estrone, and 17alpha-ethynylestradiol, respectively, in sewage water. Enrichment factors were over 1400 after derivatisation. The repeatabilities at 50 and 600ngL(-1) were better than 10% and 6%, respectively.

Publishing year

2008

Language

English

Pages

1-8

Publication/Series

Journal of Chromatography A

Volume

1192

Issue

1

Document type

Journal article

Publisher

Elsevier

Topic

  • Analytical Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 0021-9673