Antiproliferative effects of peracetylated naphthoxylosides.
Author
Summary, in English
The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.
Department/s
Publishing year
2009
Language
English
Pages
1763-1766
Publication/Series
Bioorganic & Medicinal Chemistry Letters
Volume
19
Links
Document type
Journal article
Publisher
Elsevier
Topic
- Medicinal Chemistry
Status
Published
Research group
- Glycobiology
ISBN/ISSN/Other
- ISSN: 0960-894X