Co-circulation of several similar but unique HIV-1 recombinant forms in Guinea-Bissau revealed by near full-length genomic sequencing.

Summary, in English

The dynamic HIV-1 epidemic has resulted in the emergence of several different subtypes and recombinant forms that may differ in biological properties. A recombinant form of CRF02_AG and sub-subtype A3 (A3/02) was recently described based on env sequencing and associated with faster disease progression rates compared with its parental strains. Here, we performed near full-length sequencing of the A3/02 variant to characterize the recombination patterns of a potential novel and more pathogenic circulating recombinant form of HIV-1 in Guinea-Bissau.

• Author: Angelica Palm; Joakim Esbjörnsson; Fredrik Månsson; Antonio Jamie Biague; Zacarias José da Silva; Hans Norrgren; Marianne Jansson; Patrik Medstrand
• Department/s: Division of Hematology and Transfusion Medicine; Clinical Virology, Malmö; Infectious Diseases Research Unit; Infection Medicine (BMC); Division of Medical Microbiology; EpiHealth: Epidemiology for Health
• Publishing year: 2015
• Language: English
• Pages: 938-945
• Publication/Series: AIDS Research and Human Retroviruses
• Volume: 31
• Issue: 9
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26066756?dopt=Abstract; http://dx.doi.org/10.1089/AID.2015.0073
• Document type: Journal article
• Publisher: Mary Ann Liebert, Inc.
• Topic: Infectious Medicine
• Status: Published
• Research group: Clinical Virology, Malmö; Infectious Diseases Research Unit
• ISBN/ISSN/Other: ISSN: 1931-8405