Lipids changes in liver cancer
Author
Summary, in English
Liver is one of the most important organs in energy metabolism. Most plasma apolipoproteins and endogenous lipids and lipoproteins are synthesized in the liver. It depends on the integrity of liver cellular function, which ensures homeostasis of lipid and lipoprotein metabolism. When liver cancer occurs, these processes are impaired and the plasma lipid and lipoprotein patterns may be changed. Liver cancer is the fifth common malignant tumor worldwide, and is closely related to the infections of hepatitis B virus (HBV) and hepatitis C virus (HCV). HBV and HCV infections are quite common in China and other Southeast Asian countries. In addition, liver cancer is often followed by a procession of chronic hepatitis or cirrhosis, so that hepatic function is damaged obviously on these bases, which may significantly influence lipid and lipoprotein metabolism in vivo. In this review we summarize the clinical significance of lipid and lipoprotein metabolism under liver cancer.
Department/s
Publishing year
2007
Language
English
Pages
398-409
Publication/Series
Journal of Zhejiang University-Science B
Volume
8
Issue
6
Document type
Journal article review
Publisher
Zhejiang University Press
Topic
- Medicinal Chemistry
- Pharmacology and Toxicology
Keywords
- Lipids
- Liver cancer
- Lipoprotein
Status
Published
ISBN/ISSN/Other
- ISSN: 1862-1783