RNA interference screening to detect targetable molecules in hematopoietic stem cells.
Author
Summary, in English
The molecular principles regulating hematopoietic stem cells (HSCs) remain incompletely defined. In this review, we will discuss how RNA interference (RNAi) screening has emerged as a new and powerful tool to molecularly dissect various functional aspects of both normal and malignant HSCs, and how this may ultimately enable the discovery of novel therapeutic targets for clinical applications.
Department/s
Publishing year
2014
Language
English
Pages
283-288
Publication/Series
Current Opinion in Hematology
Volume
21
Issue
4
Links
Document type
Journal article review
Publisher
Lippincott Williams & Wilkins
Topic
- Hematology
Status
Published
ISBN/ISSN/Other
- ISSN: 1531-7048