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NMD and microRNA expression profiling of the HPCX1 locus reveal MAGEC1 as a candidate prostate cancer predisposition gene.

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Author

  • Henna Mattila
  • Martin Schindler
  • Jarkko Isotalo
  • Tarja Ikonen
  • Mauno Vihinen
  • Hannu Oja
  • Teuvo L J Tammela
  • Tiina Wahlfors
  • Johanna Schleutker

Summary, in English

Several predisposition loci for hereditary prostate cancer (HPC) have been suggested, including HPCX1 at Xq27-q28, but due to the complex structure of the region, the susceptibility gene has not yet been identified.

Publishing year

2011

Language

English

Publication/Series

BMC Cancer

Volume

11

Document type

Journal article

Publisher

BioMed Central (BMC)

Topic

  • Cancer and Oncology

Keywords

  • MicroRNAs: genetics
  • Genetic Predisposition to Disease: genetics
  • Genetic Loci: genetics
  • Neoplasm: genetics
  • Antigens
  • X: genetics
  • Human
  • Chromosomes
  • Neoplasm Proteins: genetics
  • Nonsense Mediated mRNA Decay: genetics
  • Prostatic Neoplasms: genetics
  • Prostatic Neoplasms: pathology

Status

Published

ISBN/ISSN/Other

  • ISSN: 1471-2407