Aerosol characterization in real life and a methodology for human exposure studies in controlled chamber settings
Summary, in English
We have conducted time-resolved particle measurements in several homes which confirm this. From these measurements, we have been able to show just how much occupants' activities affect the indoor concentration of ultrafine particles compared to outdoor concentrations. We have also estimated e.g. total integrated daily exposure. Exposure and emission measurements have also been conducted at a carbon nanotube producing facility, and a method for counting particles containing carbon nanotubes has been suggested and validated.
Why certain particles are more dangerous than others is often investigated in animal exposure studies, where exposure levels are unrealistically high. For several reasons, the results of such studies are not simple to translate to the human system. To increase our understanding of which particle properties can cause effects in humans, a methodology for conducting human exposure studies have been developed and validated. In a controlled chamber we have exposed human test subjects to normal concentrations of common particle types; candle smoke, particles from terpene–ozone reactions and welding fume. Together with medical expertise, we have been looking for effects of these exposures. By using non-invasive tests (e.g. urine and blood samples and ECG) biochemical markers of exposure, and changes in heart rate variability (HRV) have been studied. A significant increase in the high frequency domain of the HRV during exopsure for candle smoke was found.
- Production Engineering, Human Work Science and Ergonomics
- human exposure study
- ultrafine particles
- aerosol generation
- aerosol characterization
- ISBN: 978-91-7473-857-5
21 February 2014
Lecture hall, Stora Hörsalen, IKDC, Sölvegatan 26, Lund University Faculty of Engineering
- Tareq Hussein