Laschiatrion, a new antifungal agent from a Favolaschia species (Basidiomycetes) active against human pathogens

Summary, in English

Laschiatrion (1), a new antifungal antibiotic, was isolated from fermentations of Favolaschia sp. 87129. (1) exhibits broad in vitro activity against several human pathogens while no antibacterial and cytotoxic activities could be detected. The structure was elucidated by spectroscopic techniques. As to our knowledge laschiatrion possesses a new steroid skeleton.

• Author: T Anke; A Werle; R B Kappe; Olov Sterner
• Department/s: Centre for Analysis and Synthesis
• Publishing year: 2004
• Language: English
• Pages: 496-501
• Publication/Series: Journal of Antibiotics
• Volume: 57
• Issue: 8
• Links: http://www.antibiotics.or.jp/journal/contents/vol-57/full_text/57-8/ja57_0496.pdf
• Document type: Journal article
• Publisher: Japan Antibiotics Research Association
• Topic: Organic Chemistry
• Status: Published
• ISBN/ISSN/Other: ISSN: 0021-8820