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Smooth muscle in tissue remodeling and hyper-reactivity: Airways and arteries.

På svenska

Author

Summary, in English

Smooth muscle comprises a key functional component of both the airways and their supporting vasculature. Dysfunction of smooth muscle contributes to and exacerbates a host of breathing-associated pathologies such as asthma, chronic obstructive pulmonary disease and pulmonary hypertension. These diseases may be marked by airway and/or vascular smooth muscle hypertrophy, proliferation and hyper-reactivity, and related conditions such as fibrosis and extracellular matrix remodeling. This review will focus on the contribution of airway or vascular smooth dysfunction to common airway diseases.

Department/s

Publishing year

2013

Language

English

Pages

13-23

Publication/Series

Pulmonary Pharmacology & Therapeutics

Volume

26

Issue

1

Document type

Journal article review

Publisher

Elsevier

Topic

  • Cell and Molecular Biology

Status

Published

Research group

  • Lung Biology

ISBN/ISSN/Other

  • ISSN: 1522-9629