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Monitoring of atherosclerosis

Author

  • VS Zhdanov
  • Nils Sternby

Summary, in English

Population-based epidemiological studies of atherosclerosis using autopsy material is now impossible to perform in most countries due to declining autopsy rates. Based on epidemiological studies of atherosclerosis using autopsy material in five European cities which were carried out with an interval of 25 years in the 1960s and 1980s, respectively, we have shown that atherosclerosis in young so-called practically healthy people, 20-39 years of age, who died from accidental causes, closely reflects the level of atherosclerosis in the population as a whole. These people can thus be used for monitoring the development of atherosclerosis in a population since they are normally a subject to a medico-legal autopsy; therefore, material for such studies can be obtained. Furthermore, histomorphological studies of specimens that are taken from practically healthy people at standard places of coronary arteries and aortas also reflect this general level of atherosclerosis. These studies also provide information on the atherosclerotic process and its relation to various risk factors. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

Department/s

Publishing year

2004

Language

English

Pages

39-42

Publication/Series

International Journal of Cardiology

Volume

95

Issue

1

Document type

Journal article

Publisher

Elsevier

Topic

  • Cardiac and Cardiovascular Systems

Keywords

  • monitoring
  • autopsy
  • atherosclerosis
  • epidemiology

Status

Published

Research group

  • Pathology, Malmö

ISBN/ISSN/Other

  • ISSN: 0167-5273