IL-25 Inhibits Atherosclerosis Development in Apolipoprotein E Deficient Mice.

Summary, in English

IL-25 has been implicated in the initiation of type 2 immunity and in the protection against autoimmune inflammatory diseases. Recent studies have identified the novel innate lymphoid type 2 cells (ILC2s) as an IL-25 target cell population. The purpose of this study was to evaluate if IL-25 has any influence on atherosclerosis development in mice.

• Author: Polyxeni Mantani; Pontus Dunér; Eva Bengtsson; Ragnar Alm; Irena Ljungcrantz; Ingrid Söderberg; Lena Sundius; Fong To; Jan Nilsson; Harry Björkbacka; Gunilla Nordin Fredrikson
• Department/s: Cardiovascular Research - Immunity and Atherosclerosis; EXODIAB: Excellence of Diabetes Research in Sweden; EpiHealth: Epidemiology for Health
• Publishing year: 2015
• Language: English
• Publication/Series: PLoS ONE
• Volume: 10
• Issue: 1
• Full text: - 3 MB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25629516?dopt=Abstract; http://dx.doi.org/10.1371/journal.pone.0117255
• Document type: Journal article
• Publisher: Public Library of Science (PLoS)
• Topic: Cardiac and Cardiovascular Systems
• Status: Published
• Research group: Cardiovascular Research - Immunity and Atherosclerosis
• ISBN/ISSN/Other: ISSN: 1932-6203