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Microarray-based cancer diagnosis with artificial neural networks

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Author

Summary, in English

In recent years, the advent of experimental methods top robe gene expression profiles of cancer on a genome-wide scale has led to widespread use of supervised machine learning algorithms to characterize these profiles. The main applications of these analysis methods range from assigning functional classes of previously uncharacterized genes to classification and prediction of different cancer tissues. This article surveys the application of machine learning algorithms to classification and diagnosis of cancer based on expression profiles. To exemplify the important issues of the classification procedure, the emphasis of this article is on one such method, namely artificial neural networks. In addition, methods to extract genes that are important for the performance of a classifier, as well as the influence of sample selection on prediction results are discussed.

Publishing year

2003-03

Language

English

Pages

30-30

Publication/Series

BioTechniques

Volume

34

Issue

Suppl

Document type

Journal article review

Publisher

Informa Healthcare

Topic

  • Bioinformatics and Systems Biology

Status

Published

ISBN/ISSN/Other

  • ISSN: 0736-6205