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Characterization of probe contact effects on diffuse reflectance spectroscopy measurements

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Author

Summary, in English

Diffuse reflectance spectroscopy (DRS) is a rapid, non-invasive optical method widely adopted to gain diagnostic information of tissue. The most flexible approach to this method is a fiber-optic contact-probe used with a spectroscopy system. A challenge of this method is that the external pressure brought by the probe can significantly affect the tissue optical properties as well as the light coupling into the probe, and thus influence the collected DRS-spectrum. In this study we investigate and characterize the effect of probe pressure on DRS-spectra obtained with a calibrated loaded-spring system used with a fiber optic probe in the range (400 – 1600) nm. A multilayer FE-model of the indentation is developed to get a better insight of the distribution of pressure and stresses inside the skin under indentation.

Publishing year

2015

Language

English

Pages

953143-953143

Publication/Series

BioPhotonics South America (SPIE Proceedings)

Volume

9531

Document type

Conference paper

Publisher

SPIE

Topic

  • Atom and Molecular Physics and Optics
  • Applied Mechanics

Keywords

  • Diffuse reflectance spectroscopy
  • probe contact pressure
  • finite element simulation
  • biomechanical
  • tissue optical properties.

Conference name

Joint Meeting of the 1st SPIE Conference on Biophotonics South America (BSA) / 15th World Congress of the International-Photodynamic-Association (IPA)

Conference date

2015-05-23 - 2015-05-25

Conference place

Rio de Janeiro, Brazil

Status

Published

Research group

  • Biophotonics

ISBN/ISSN/Other

  • ISSN: 0277-786X
  • ISSN: 1996-756X