EpiHealth: a large population-based cohort study for investigation of gene-lifestyle interactions in the pathogenesis of common diseases
Author
Summary, in English
The most common diseases affecting middle-aged and elderly subjects in industrialized countries are multigenetic and lifestyle related. Several attempts have been made to study interactions between genes and lifestyle factors, but most such studies lack the power to examine interactions between several genes and several lifestyle components. The primary objective of the EpiHealth cohort study is to provide a resource to study interactions between several genotypes and lifestyle factors in a large cohort (the aim is 300,000 individuals) derived from the Swedish population in the age range of 45-75 years regarding development of common degenerative disorders, such as cardiovascular diseases, cancer, dementia, joint pain, obstructive lung disease, depression, and osteoporotic fractures. The study consists of three parts. First, a collection of data on lifestyle factors by self-assessment using an internet-based questionnaire. Second, a visit to a test center where blood samples are collected and physiological parameters recorded. Third, the sample is followed for occurrence of outcomes using nationwide medical registers. This overview presents the study design and some baseline characteristics from the first year of data collection in the EpiHealth study.
Department/s
Publishing year
2013
Language
English
Pages
189-197
Publication/Series
European Journal of Epidemiology
Volume
28
Issue
2
Document type
Journal article
Publisher
Springer
Topic
- Public Health, Global Health, Social Medicine and Epidemiology
Keywords
- Epidemiology
- Lifestyle
- Gene
- Prospective
- Cohort study
Status
Published
Research group
- Geriatrics
- Geriatric Medicine
- Internal Medicine - Epidemiology
ISBN/ISSN/Other
- ISSN: 1573-7284