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Health-related quality of life during the last three months of life in patients with advanced cancer

Author

  • Marianne Ahlner-Elmqvist
  • Marit S. Jordhoy
  • Kristin Bjordal
  • Stein Kaasa
  • Magnus Jannert

Summary, in English

The aim of the study was to explore the development of functioning impairments and symptom occurrence during the last months of life of advanced cancer patients. Self-reported data from 116 patients who all completed the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) at 3, 2 and 1 month before death were analysed. All functioning aspects deteriorated. For physical, cognitive and social function, the most marked changes occurred between 2 and 1 month before death. The proportion reporting serious difficulties with self-care activities increased from 14% to 43%. The most seriously affected activity could not be distinguished from the EORTC QLQ-C30 scores. Levels of fatigue, dyspnoea and appetite loss increased significantly. More than 50% of the patients had severe pain at all assessments, and only a minor number (8%) reported any improvement. The findings have implications for the planning of care and indicate that further research is required to improve assessment, treatment and follow-up procedures. Adequate pain treatment seems still to be a challenge. Anorexia, fatigue as well as dyspnoea are all symptoms that need further focus.

Publishing year

2009

Language

English

Pages

191-198

Publication/Series

Supportive Care in Cancer

Volume

17

Issue

2

Document type

Journal article

Publisher

Springer

Topic

  • Cancer and Oncology

Keywords

  • Self-assessment questionnaires
  • Cancer
  • EORTC QLQ-C30
  • Palliative care
  • Health-related quality of life
  • End of life

Status

Published

Research group

  • Laryngoesophagology, Allergy and Life Quality

ISBN/ISSN/Other

  • ISSN: 0941-4355