Impact of combinations of antineoplastic drugs on intestinal microflora in 9 patients with leukaemia.

Summary, in English

The impact of antineoplastic drugs on the intestinal microflora was studied in 9 patients with acute leukaemia during chemotherapy and in 5 patients also during chemotherapy-induced neutropenia. Quantitative and qualitative microbiological analyses of faecal samples obtained before and during chemotherapy showed significantly increased counts of Bacteroides spp. in 3/9 patients and, during neutropenia, significantly increased counts of yeasts in 2/5 patients; however, the intestinal microflora was stable in most patients.

• Author: Anna Nyhlén; Bengt Ljungberg; Ingrid Nilsson-Ehle; Carl Erik Nord
• Department/s: Section III
• Publishing year: 2002
• Language: English
• Pages: 17-21
• Publication/Series: Scandinavian Journal of Infectious Diseases
• Volume: 34
• Issue: 1
• Links: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=PubMed&Cmd=ShowDetailView&TermToSearch=11874159&ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum; http://dx.doi.org/10.1080/00365540110076994
• Document type: Journal article
• Publisher: Informa Healthcare
• Topic: Infectious Medicine
• Status: Published
• ISBN/ISSN/Other: ISSN: 1651-1980