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A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients

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Author

  • K Bjordal
  • A de Graeff
  • P M Fayers
  • E Hammerlid
  • C van Pottelsberghe
  • D Curran
  • Marianne Ahlner-Elmqvist
  • E J Maher
  • J W Meyza
  • A Bredart
  • A L Soderholm
  • J J Arraras
  • J S Feine
  • H Abendstein
  • R P Morton
  • T Pignon
  • P Huguenin
  • A Bottomly
  • S Kaasa
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Summary, in English

This study tests the reliability and validity of the European Organization for Research and Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H&N35) and version 3.0 of the EORTC Core Questionnaire (QLQ-C30) in 622 head and neck cancer patients from 12 countries. The patients completed the QLQ-C30, the QLQ-H&N35 and a debriefing questionnaire before antineoplastic treatment or at a follow-up. 232 patients receiving treatment completed a second questionnaire after treatment. Compliance was high and the questionnaire was well accepted by the patients. Multitrait scaling analysis confirmed the proposed scale structure of the QLQ-H&N35. The QLQ-H&N35 was responsive to differences between disease status, site and patients with different Karnofsky performance status, and to changes over time. The new physical functioning scale (with a four-point response format) of version 3.0 of the QLQ-C30 was shown to be more reliable than previous versions. Thus, the QLQ-H&N35, in conjunction with the QLQ-C30, appears to be reliable, valid and applicable to broad multicultural samples of head and neck cancer patients.

Publishing year

2000

Language

English

Pages

1796-1807

Publication/Series

European Journal of Cancer

Volume

36

Issue

14

Document type

Journal article

Publisher

Elsevier

Topic

  • Otorhinolaryngology

Keywords

  • EORTC QLQ-H&N35
  • EORTC QLQ-C30
  • Validation
  • Questionnaire
  • Assessment
  • Head and neck cancer
  • Quality of life

Status

Published

Research group

  • Laryngoesophagology, Allergy and Life Quality

ISBN/ISSN/Other

  • ISSN: 1879-0852