Mucosal glucagon-like peptide-1 and gastric inhibitory polypeptide cell numbers in the super-obese human foregut after gastric bypass.

Summary, in English

Super-obesity, a body mass index>50 kg/m(2), is difficult to treat. Many studies have focused on the anatomic changes of the intestines; the physiologic background is not clearly identified. It is established that Roux-en-Y gastric bypass (RYGB) augments secretion of glucagon-like peptide-1 (GLP-1), peptide tyrosine tyrosine (PYY), and insulin, but other aspects of gut hormone cell function in the alimentary limb are unknown.

• Author: Bent J Nergård; Andreas Lindqvist; Hjörtur G Gislason; Leif Groop; Mikael Ekelund; Nils Wierup; Jan Hedenbro
• Department/s: Neuroendocrine Cell Biology; Translational Muscle Research; Surgery (Lund); EXODIAB: Excellence of Diabetes Research in Sweden
• Publishing year: 2015
• Language: English
• Pages: 1237-1246
• Publication/Series: Surgery for Obesity and Related Diseases
• Volume: 11
• Issue: 6
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26143297?dopt=Abstract; http://dx.doi.org/10.1016/j.soard.2015.03.021
• Document type: Journal article
• Publisher: Elsevier
• Topic: Surgery
• Status: Published
• Research group: Neuroendocrine Cell Biology; Genomics, Diabetes and Endocrinology
• ISBN/ISSN/Other: ISSN: 1550-7289