Biological effects and clinical efficacy of a topical Toll-like receptor 7 agonist in seasonal allergic rhinitis: a parallel group controlled phase IIa study.

Summary, in English

The purpose of the study was to examine effects of pre-treatment with a Toll-like receptor 7 (TLR7) agonist (AZD8848) in allergic rhinitis and to evaluate clinical effects of two dosing regimens.

• Author: Lennart Greiff; Cecilia Ahlström-Emanuelsson; Mikaela Alenäs; Gun Almqvist; Morgan Andersson; Anders Cervin; Jan Dolata; Sam Lindgren; Anders S Mårtensson; Barbara Young; Henrik Widegren
• Department/s: Otorhinolaryngology (Lund); Clinical Sciences, Helsingborg
• Publishing year: 2015
• Language: English
• Pages: 903-915
• Publication/Series: Inflammation Research
• Volume: 64
• Issue: 11
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26342289?dopt=Abstract; http://dx.doi.org/10.1007/s00011-015-0873-2
• Document type: Journal article
• Publisher: Birkhäuser Verlag
• Topic: Respiratory Medicine and Allergy
• Status: Published
• ISBN/ISSN/Other: ISSN: 1420-908X