Intensified Tuberculosis Case-Finding in HIV-Positive Adults Managed at Ethiopian Health Centers: Diagnostic Yield of Xpert MTB/RIF Compared with Smear Microscopy and Liquid Culture.

Summary, in English

Detection of active tuberculosis (TB) before antiretroviral therapy (ART) initiation is important, but optimal diagnostic methods for use in resource-limited settings are lacking. We assessed the prevalence of TB, evaluated the diagnostic yield of Xpert MTB/RIF in comparison with smear microscopy and culture, and the impact of Xpert results on clinical management in HIV-positive adults eligible for ART at health centers in a region of Ethiopia.

• Author: Taye Balcha; Erik Sturegård; Niclas Winqvist; Sten Skogmar; Anton Reepalu; Zelalem Habtamu Jemal; Gudeta Tibesso; Thomas Schön; Per Björkman
• Department/s: Infectious Diseases Research Unit; Clinical Microbiology, Malmö
• Publishing year: 2014
• Language: English
• Publication/Series: PLoS ONE
• Volume: 9
• Issue: 1
• Full text: - 301 kB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/24465572?dopt=Abstract; http://dx.doi.org/10.1371/journal.pone.0085478
• Document type: Journal article
• Publisher: Public Library of Science (PLoS)
• Topic: Microbiology in the medical area; Infectious Medicine
• Status: Published
• Research group: Infectious Diseases Research Unit; Clinical Microbiology, Malmö
• ISBN/ISSN/Other: ISSN: 1932-6203