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Current progress of adhesins as vaccine candidates for Moraxella catarrhalis

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Author

Summary, in English

Moraxello catorrhalis is an emerging pathogen and all isolates are now considered beta-lactamase producing. Potential further use of vaccines against Streptococcus pneumoniae and nontypeable Haemophilus influenzae means that M. catarrhalis might be thrust further into the limelight. However, a vaccine has not yet been designed. In this review, the progress of M. catarrhalis adhesins as vaccine candidates is discussed with a focus on various candidate antigens that spanned those discovered more than 10 years ago, for example, the ubiquitous surface proteins to newer antigens, such as the Moraxella IgD-binding hemagglutinin.

Publishing year

2007

Language

English

Pages

949-956

Publication/Series

Expert Review of Vaccines

Volume

6

Issue

6

Document type

Journal article review

Publisher

Future Drugs Ltd

Topic

  • Microbiology in the medical area

Keywords

  • surface protein A1/A2
  • ubiquitous
  • outer membrane protein CD
  • OLpA
  • IgD binding protein/hag
  • Moraxella
  • Moraxella catarrhalis
  • mcmA
  • filamentous hemagglutinin
  • McaP

Status

Published

Research group

  • Clinical Microbiology, Malmö

ISBN/ISSN/Other

  • ISSN: 1744-8395