The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients.

Summary, in English

The human Sushi Domain-Containing Protein 4 (SUSD4) was recently shown to function as a novel inhibitor of the complement system, but its role in tumor progression is unknown.

• Author: Emelie Englund; Bart Reitsma; Ben King; Astrid Escudero Esparza; Sioned Owen; Akira Orimo; Marcin Okroj; Theano Anagnostaki; Wen G Jiang; Karin Jirström; Anna Blom
• Department/s: Protein Chemistry, Malmö; Pathology, Malmö; Tumor microenvironment; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publishing year: 2015
• Language: English
• Publication/Series: BMC Cancer
• Volume: 15
• Full text: - 2 MB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26480818?dopt=Abstract; http://dx.doi.org/10.1186/s12885-015-1734-7
• Document type: Journal article
• Publisher: BioMed Central (BMC)
• Topic: Cancer and Oncology
• Status: Published
• Research group: Protein Chemistry, Malmö; Pathology, Malmö
• ISBN/ISSN/Other: ISSN: 1471-2407