Induced Hematopoietic Stem Cells: Unlocking Restrictions in Lineage Potential and Self-renewal.

Summary, in English

Obtaining sufficient numbers of immunologically matched hematopoietic stem cells (HSCs) poses a major clinical hurdle in bone marrow transplantation therapies. In a recent study in Cell, Riddell et al. (2014) generate induced HSCs from differentiated blood cells, which may serve as a potential solution to this clinical challenge.

• Author: Martin Wahlestedt; David Bryder
• Department/s: Department of Experimental Medical Science; StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
• Publishing year: 2014
• Language: English
• Pages: 555-556
• Publication/Series: Cell Stem Cell
• Volume: 14
• Issue: 5
• Links: http://www.ncbi.nlm.nih.gov/pubmed/24792111?dopt=Abstract; http://dx.doi.org/10.1016/j.stem.2014.04.008
• Document type: Journal article (comment)
• Publisher: Cell Press
• Topic: Cell Biology
• Status: Published
• ISBN/ISSN/Other: ISSN: 1934-5909