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Synthesis of aromatic C-xylosides by position inversion of glucose

Author

Summary, in English

Two formally C-xylosylated analogs to 2-naphthyl beta-D-xylopyranoside, which is known to initiate priming of glucosaminoglycan chains, were synthesized by a position inversion of glucose (i.e., position I becomes position 5). The D-C-xyloside showed priming, while the L-C-xyloside did not initiate priming. (c) 2006 Elsevier Ltd. All rights reserved.

Publishing year

2006

Language

English

Pages

6659-6665

Publication/Series

Bioorganic & Medicinal Chemistry

Volume

14

Issue

19

Document type

Journal article

Publisher

Elsevier

Topic

  • Medicinal Chemistry

Keywords

  • structure-activity relationships
  • C-glycosides
  • carbohydrates
  • xylose

Status

Published

Research group

  • Glycobiology

ISBN/ISSN/Other

  • ISSN: 0968-0896