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Assessment of contractile and noncontractile components in human skeletal muscle by magnetic resonance imaging.

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Author

  • Anna Maria Drake
  • Krister Askaner
  • Stig Holtås
  • David Downham
  • Jan Lexell

Summary, in English

A magnetic resonance imaging (MRI) technique for the assessment of contractile and noncontractile components of human skeletal muscle is described, and the inter-rater and intra-rater test-retest reliability for repeated measurements from the same MR image are examined. Twenty cross-sectional MR images from the right lower leg were obtained from 30 healthy young men and women (mean age 24.1 years, SD 3.3). The anatomical cross-sectional area (aCSA; cm2), the cross-sectional area of noncontractile components (Noncon; cm2), the contractile cross-sectional area (cCSA = aCSA minus Noncon; cm2), and the relative amount of Noncon (%), of the ankle dorsiflexor muscle compartment were determined for each slice using a computer-based image analysis system. Reliability for repeated measurements of the slice with the largest aCSA for the 30 subjects was analyzed by two raters on two different occasions. Inter-rater reliability on both occasions, assessed by the intraclass correlation coefficient (ICC), was excellent for cCSA (ICC3.1 = 0.99) and Noncon (ICC(3.1)

Publishing year

2002

Language

English

Pages

251-258

Publication/Series

Muscle and Nerve

Volume

25

Issue

2

Document type

Journal article

Publisher

John Wiley & Sons Inc.

Topic

  • Physiotherapy
  • Radiology, Nuclear Medicine and Medical Imaging

Keywords

  • Magnetic Resonance Imaging
  • Male
  • Muscle Skeletal : anatomy & histology : physiology
  • Observer Variation
  • Support Non-U.S. Gov't
  • Image Processing Computer-Assisted
  • Ankle
  • Female
  • Human
  • Adult

Status

Published

Research group

  • Human Movement: health and rehabilitation

ISBN/ISSN/Other

  • ISSN: 0148-639X