The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia

På svenska

Author

  • D. Hoogewijs
  • N. B. Terwilliger
  • K. A. Webster
  • J. A. Powell-Coffman
  • S. Tokishita
  • H. Yamagata
  • T. Hankeln
  • T. Burmester
  • K. T. Rytkonen
  • M. Nikinmaa
  • D. Abele
  • K. Heise
  • M. Lucassen
  • J. Fandrey
  • R. H. Maxwell
  • Sven Påhlman
  • T. A. Gorr
Show all

Summary, in English

The objective of this symposium at the First International Congress of Respiratory Biology (ICRB) was to enhance communication between comparative biologists and cancer researchers working on O-2 sensing via the HIF pathway. Representatives from both camps came together on August 13-16, 2006, in Bonn, Germany, to discuss molecular adaptations that occur after cells have been challenged by a reduced (hypoxia) or completely absent (anoxia) supply of oxygen. This brief "critters-to-cancer" survey discusses current projects and new directions aimed at improving understanding of hypoxic signaling and developing therapeutic interventions.

Publishing year

2007

Language

English

Pages

552-577

Publication/Series

Integrative and Comparative Biology

Volume

47

Issue

4

Document type

Journal article

Publisher

Oxford University Press

Topic

  • Cancer and Oncology

Status

Published

ISBN/ISSN/Other

  • ISSN: 1557-7023