Plasma homocysteine in 80-year-olds Relationships to medical, psychological and social variables.

Summary, in English

Plasma homocysteine concentrations in a group of 80-year-old persons were related to symptoms and signs. Plasma homocysteine concentrations higher than 15 mumol/l were associated with lower total life satisfaction (P<0.01), mood (P<0.05), zest for life (P<0.05), lower scores for reasoning (P<0.05), spatial ability (P<0.05), memory recognition (P<0.05), and subjective health (P<0.01). In an instrument comprising of 30 symptoms, plasma homocysteine concentrations higher than 15 mumol/l were associated with impaired concentration (P<0.05), restlessness (P<0.05), feeling cold (P<0.05), loss of weight (P<0.05), and feeling depressed (P<0.01). The above data indicate that plasma homocysteine values over 15 mumol/l could be relevant markers for clinical intervention.

• Author: E Jensen; Ove Dehlin; Eva Marie Erfurth; Bo Hagberg; Gillis Samuelsson; Torbjörn Svensson; Björn Hultberg
• Department/s: Geriatric Medicine; Medicine, Lund; Department of Psychology; Sustainable occupations and health in a life course perspective; Division of Clinical Chemistry and Pharmacology
• Publishing year: 1998
• Language: English
• Pages: 215-226
• Publication/Series: Archives of Gerontology and Geriatrics
• Volume: 26
• Issue: 3
• Links: http://www.ncbi.nlm.nih.gov/pubmed/18653138; http://www.sciencedirect.com/science/article/pii/S0167494398000041; http://dx.doi.org/10.1016/S0167-4943(98)00004-1
• Document type: Journal article
• Publisher: Elsevier
• Topic: Gerontology, specializing in Medical and Health Sciences
• Status: Published
• Research group: Geriatric Medicine; Sustainable occupations and health in a life course perspective
• ISBN/ISSN/Other: ISSN: 1872-6976