The clinical significance of BRAF and NRAS mutations in a clinic-based metastatic melanoma cohort.

Summary, in English

BRAF and NRAS mutations are frequently found in melanoma tumours and recently developed BRAF targeted therapies demonstrate significant clinical benefit.

• Author: Henrik Ekedahl; Helena Cirenajwis; Katja Harbst; Ana Carneiro; Kari Nielsen; Håkan Olsson; L Lundgren; Christian Ingvar; Gunilla Jönsson
• Department/s: Breastcancer-genetics; Surgery (Lund); Dermatology and Venereology (Lund); Cell Pathology, Malmö; Melanoma Genomics; EpiHealth: Epidemiology for Health; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publishing year: 2013
• Language: English
• Pages: 1049-1055
• Publication/Series: British Journal of Dermatology
• Volume: 169
• Issue: 5
• Links: http://www.ncbi.nlm.nih.gov/pubmed/23855428?dopt=Abstract; http://dx.doi.org/10.1111/bjd.12504
• Document type: Journal article
• Publisher: Wiley-Blackwell
• Topic: Dermatology and Venereal Diseases
• Status: Published
• Research group: Cell Pathology, Malmö; Melanoma Genomics
• ISBN/ISSN/Other: ISSN: 1365-2133