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Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Human C1q Deficiency: The Karolinska Experience.

På svenska

Author

  • Richard F Olsson
  • Stefan Hagelberg
  • Bodil Schiller
  • Olle Ringdén
  • Lennart Truedsson
  • Anders Åhlin

Summary, in English

Human C1q deficiency is associated with systemic lupus erythematosus (SLE) and increased susceptibility to severe bacterial infections. These patients require extensive medical therapy and some develop treatment-resistant disease. Because C1q is produced by monocytes, it has been speculated that allogeneic hematopoietic stem cell transplantation (allo-HSCT) may cure this disorder.

Publishing year

2015-10-29

Language

English

Publication/Series

Transplantation

Document type

Journal article

Publisher

Lippincott Williams & Wilkins

Topic

  • Rheumatology and Autoimmunity

Status

Published

ISBN/ISSN/Other

  • ISSN: 1534-6080