The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

A novel blood-based biomarker for detection of autism spectrum disorders.

På svenska

Author

  • Momeni N
  • Bergquist J
  • Behnia F
  • Bengt Sivberg
  • Joghataei M. T.
  • Persson B. L.

Summary, in English

Autism spectrum disorders (ASD) are classified as neurological developmental disorders. Several studies have been carried out to find a candidate biomarker linked to the development of these disorders, but up to date no reliable biomarker is available. Mass spectrometry techniques have been used for protein profiling of blood plasma of children with such disorders in order to identify proteins/peptides that may be used as biomarkers for detection of the disorders. Three differentially expressed peptides with mass-charge (m/z) values of 2020 ± 1, 1864 ± 1 and 1978 ± 1 Da in the heparin plasma of children with ASD that were significantly changed as compared with the peptide pattern of the non-ASD control group are reported here. This novel set of biomarkers allows for a reliable blood-based diagnostic tool that may be used in diagnosis and potentially, in prognosis of ASD

Publishing year

2012

Language

English

Pages

91-91

Publication/Series

Translational Psychiatry

Volume

2

Issue

3

Document type

Journal article

Publisher

Nature Publishing Group

Topic

  • Health Sciences

Status

Published

Research group

  • Integrative Health Research

ISBN/ISSN/Other

  • ISSN: 2158-3188