Combined Androgen and Estrogen Receptor Status in Breast Cancer: Treatment Prediction and Prognosis in a Population-based Prospective Cohort.

Summary, in English

To evaluate whether tumor androgen receptor (AR) expression was prognostic and/or predictive for endocrine treatment alone or in combination with estrogen receptor (ER). The AR has been hypothesized to have differential prognostic roles in breast cancer depending on tumor ER-status, and to influence endocrine treatment response.

• Author: Karin Elebro; Signe Borgquist; Maria Simonsson; Andrea Markkula; Karin Jirström; Christian Ingvar; Carsten Rose; Helena Jernström
• Department/s: Epidemiology and pharmacogenetics; Breast cancer prevention & intervention; Breastcancer-genetics; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation; Tumor microenvironment; Surgery (Lund)
• Publishing year: 2015
• Language: English
• Pages: 3640-3650
• Publication/Series: Clinical Cancer Research
• Volume: 21
• Issue: 16
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25904752?dopt=Abstract; http://dx.doi.org/10.1158/1078-0432.CCR-14-2564
• Document type: Journal article
• Publisher: American Association for Cancer Research
• Topic: Cancer and Oncology
• Status: Published
• Research group: Epidemiology and pharmacogenetics; Breast cancer prevention & intervention
• ISBN/ISSN/Other: ISSN: 1078-0432