Dermatan sulfate epimerase 1 deficient mice as a model for human abdominal wall defects.

Summary, in English

Dermatan sulfate (DS) is a highly sulfated polysaccharide with a variety of biological functions in extracellular matrix organization and processes such as tumorigenesis and wound healing. A distinct feature of DS is the presence of iduronic acid, produced by the two enzymes, DS-epimerase 1 and 2, which are encoded by Dse and Dsel, respectively.

• Author: Renata Gustafsson; Xanthi Stachtea; Marco Maccarana; Emma Grottling; Erik Eklund; Anders Malmström; Åke Oldberg
• Department/s: Åke Oldberg´s group; Matrix Biology; Paediatrics (Lund)
• Publishing year: 2014
• Language: English
• Pages: 712-720
• Publication/Series: Birth Defects Research. Part A: Clinical and Molecular Teratology
• Volume: 100
• Issue: 9
• Full text: - 4 kB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25186462?dopt=Abstract; http://dx.doi.org/10.1002/bdra.23300
• Document type: Journal article
• Publisher: John Wiley & Sons Inc.
• Topic: Obstetrics, Gynecology and Reproductive Medicine
• Status: Published
• Research group: Åke Oldberg´s group; Matrix Biology
• ISBN/ISSN/Other: ISSN: 1542-0760