The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Mechanisms for motor timing in the cerebellar cortex

På svenska

Author

Summary, in English

In classical eyeblink conditioning a subject learns to blink to a previously neutral stimulus. This conditional response is timed to occur just before an air puff to the eye. The learning is known to depend on the cerebellar cortex where Purkinje cells respond with adaptively timed pauses in their spontaneous firing. The pauses in the inhibitory Purkinje cells cause disinhibition of the cerebellar nuclei, which elicit the overt blinks. The timing of a Purkinje cell response was previously thought to require a temporal code in the input signal but recent work suggests that the Purkinje cells can learn to time their responses through an intrinsic mechanism that is activated by metabotropic glutamate receptors (mGluR7).

Publishing year

2016

Language

English

Pages

53-59

Publication/Series

Current Opinion in Behavioral Sciences

Volume

8

Document type

Journal article review

Publisher

Elsevier

Topic

  • Behavioral Sciences Biology
  • Neurosciences

Status

Published

Project

  • Thinking in Time: Cognition, Communication and Learning
  • Thinking in Time: Cognition, Communication and Learning

Research group

  • Associative Learning

ISBN/ISSN/Other

  • ISSN: 2352-1554