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Oral administration of live exopolysaccharide-producing Pediococcus parvulus, but not purified exopolysaccharide suppressed Enterobacteriaceae without affecting bacterial diversity in caecum of mice.

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Author

Summary, in English

Growing evidence indicates that the gut microbiota could have an important role in the development of diet and lifestyle induced diseases. It has been shown that modulation of the gut microbiota by means of probiotics and prebiotics could improve host health. An oat based product fermented by the exopolysaccharide (EPS)-producing Pediococcus parvulus 2.6 has been reported to have a bifidogenic effect. To find out whether the effect could be attributed to the EPS or the bacterium, mice were fed a diet supplemented with 2 % purified EPS or 10(8) CFU/g of live P. parvulus 2.6 for six weeks. Both supplementations altered the gut microbiota composition but in different directions. Purified EPS not only significantly lowered the microbial diversity (P < 0.001) but decreased the bifidobacterial population (P = 0.01). In contrast, the live EPS-producing P. parvulus 2.6 antagonized Enterobacteriaceae without disturbing the homeostasis of the caecal microbiota.

Publishing year

2013

Language

English

Pages

5030-5037

Publication/Series

Applied and Environmental Microbiology

Volume

79

Issue

16

Document type

Journal article

Publisher

American Society for Microbiology

Topic

  • Industrial Biotechnology
  • Nutrition and Dietetics

Status

Published

Project

  • ANTIDIABETIC FOOD CENTRE

ISBN/ISSN/Other

  • ISSN: 0099-2240