Regulation of Smooth Muscle Dystrophin and Synaptopodin 2 Expression by Actin Polymerization and Vascular Injury.

Summary, in English

Actin dynamics in vascular smooth muscle is known to regulate contractile differentiation and may play a role in the pathogenesis of vascular disease. However, the list of genes regulated by actin polymerization in smooth muscle remains incomprehensive. Thus, the objective of this study was to identify actin-regulated genes in smooth muscle and to demonstrate the role of these genes in the regulation of vascular smooth muscle phenotype.

• Author: Karolina Turczynska; Karl Swärd; Thi Hien Tran; Johan Wohlfahrt; Ingrid Yao Mattisson; Mari Ekman; Johan Nilsson; Johan Sjögren; Anna Hultgårdh; Pilar Cidad; Per Hellstrand; M Teresa Pérez-García; Sebastian Albinsson; Vignesh Murugesan
• Department/s: Minimal invasive cardiac surgery in valvular heart disease; Vascular Physiology; Cellular Biomechanics; Molecular Vascular Physiology; Cardiovascular Research - Immunity and Atherosclerosis; Thoracic Surgery; Artificial Intelligence and Bioinformatics in Cardiothoracic Sciences (AIBCTS); Vessel Wall Biology
• Publishing year: 2015
• Language: English
• Pages: 1489-1497
• Publication/Series: Arteriosclerosis, Thrombosis and Vascular Biology
• Volume: 35
• Issue: 6
• Full text: - 1 MB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25857312?dopt=Abstract; http://dx.doi.org/10.1161/ATVBAHA.114.305065
• Document type: Journal article
• Publisher: Lippincott Williams & Wilkins
• Topic: Cardiac and Cardiovascular Systems
• Status: Published
• Research group: Minimal invasive cardiac surgery in valvular heart disease; Vascular Physiology; Cellular Biomechanics; Molecular Vascular Physiology; Cardiovascular Research - Immunity and Atherosclerosis; Artificial Intelligence and Bioinformatics in Cardiothoracic Sciences (AIBCTS); Vessel Wall Biology
• ISBN/ISSN/Other: ISSN: 1524-4636