Metabolomic profiles of hepatocellular carcinoma in a European prospective cohort.

Summary, in English

Hepatocellular carcinoma (HCC), the most prevalent form of liver cancer, is difficult to diagnose and has limited treatment options with a low survival rate. Aside from a few key risk factors, such as hepatitis, high alcohol consumption, smoking, obesity, and diabetes, there is incomplete etiologic understanding of the disease and little progress in identification of early risk biomarkers.

• Author: Anne Fages; Talita Duarte-Salles; Magdalena Stepien; Pietro Ferrari; Veronika Fedirko; Clément Pontoizeau; Antonia Trichopoulou; Krasimira Aleksandrova; Anne Tjønneland; Anja Olsen; Françoise Clavel-Chapelon; Marie-Christine Boutron-Ruault; Gianluca Severi; Rudolf Kaaks; Tilman Kuhn; Anna Floegel; Heiner Boeing; Pagona Lagiou; Christina Bamia; Dimitrios Trichopoulos; Domenico Palli; Valeria Pala; Salvatore Panico; Rosario Tumino; Paolo Vineis; H Bas Bueno-de-Mesquita; Petra H Peeters; Elisabete Weiderpass; Antonio Agudo; Esther Molina-Montes; José María Huerta; Eva Ardanaz; Miren Dorronsoro; Klas Sjöberg; Bodil Ohlsson; Kay-Tee Khaw; Nick Wareham; Ruth C Travis; Julie A Schmidt; Amanda Cross; Marc Gunter; Elio Riboli; Augustin Scalbert; Isabelle Romieu; Benedicte Elena-Herrmann; Mazda Jenab
• Department/s: Gastroenterology; Internal Medicine - Epidemiology
• Publishing year: 2015
• Language: English
• Publication/Series: BMC Medicine
• Volume: 13
• Issue: 1
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26399231?dopt=Abstract; http://dx.doi.org/10.1186/s12916-015-0462-9
• Document type: Journal article
• Publisher: BioMed Central (BMC)
• Topic: Cancer and Oncology
• Status: Published
• Research group: Gastroenterology; Internal Medicine - Epidemiology
• ISBN/ISSN/Other: ISSN: 1741-7015