Accuracy of Brain Amyloid Detection in Clinical Practice Using Cerebrospinal Fluid β-Amyloid 42: A Cross-Validation Study Against Amyloid Positron Emission Tomography.

Summary, in English

Before adding cerebrospinal fluid (CSF) biomarkers to the diagnostic workup of Alzheimer disease, it needs to be determined whether CSF biomarkers analyzed in routine clinical practice can reliably predict cortical β-amyloid (Aβ) deposition.

• Author: Sebastian Palmqvist; Henrik Zetterberg; Kaj Blennow; Susanna Vestberg; Ulf Andreasson; David J Brooks; Rikard Owenius; Douglas Hägerström; Per Wollmer; Lennart Minthon; Oskar Hansson
• Department/s: Clinical Memory Research; Psychiatry (Lund); Clinical Neurophysiology; Clinical Physiology and Nuclear Medicine, Malmö; MultiPark: Multidisciplinary research focused on Parkinson´s disease
• Publishing year: 2014
• Language: English
• Pages: 1282-1289
• Publication/Series: JAMA Neurology
• Volume: 71
• Issue: 10
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25155658?dopt=Abstract; http://dx.doi.org/10.1001/jamaneurol.2014.1358
• Document type: Journal article
• Publisher: American Medical Association
• Topic: Neurology
• Status: Published
• Research group: Clinical Memory Research; Clinical Physiology, Malmö
• ISBN/ISSN/Other: ISSN: 2168-6157