High-Fat Diet Reduces the Formation of Butyrate, but Increases Succinate, Inflammation, Liver Fat and Cholesterol in Rats, while Dietary Fibre Counteracts These Effects.

Summary, in English

Obesity is linked to type 2 diabetes and risk factors associated to the metabolic syndrome. Consumption of dietary fibres has been shown to have positive metabolic health effects, such as by increasing satiety, lowering blood glucose and cholesterol levels. These effects may be associated with short-chain fatty acids (SCFAs), particularly propionic and butyric acids, formed by microbial degradation of dietary fibres in colon, and by their capacity to reduce low-grade inflammation.

• Author: Greta Jakobsdottir; Jie Xu; Göran Molin; Siv Ahrné; Margareta Nyman
• Department/s: Division of Food and Pharma
• Publishing year: 2013
• Language: English
• Publication/Series: PLoS ONE
• Volume: 8
• Issue: 11
• Links: http://dx.doi.org/10.1371/journal.pone.0080476
• Document type: Journal article
• Publisher: Public Library of Science (PLoS)
• Topic: Nutrition and Dietetics
• Status: Published
• Project: ANTIDIABETIC FOOD CENTRE
• ISBN/ISSN/Other: ISSN: 1932-6203