Bicyclic diols and related derivatives as catalysts for the asymmetric diethylzinc addition to benzaldehyde

Summary, in English

Chiral bicyclic diols based on bicyclo[2.2.2]octane and bicyclo[2.2.1]heptane have been synthesized and their catalytic capacity in the asymmetric diethylzinc addition to benzaldehyde compared with those described for previously synthesized 2,6-bicyclo[2.2.2]octane-diols (BODOLs). The influence of the number of coordinating sites and the distance between them were studied. (C) 2008 Elsevier Ltd. All rights reserved.

• Author: Cecilia Olsson; Annika Friberg; Torbjörn Frejd
• Department/s: Centre for Analysis and Synthesis
• Publishing year: 2008
• Language: English
• Pages: 1476-1483
• Publication/Series: Tetrahedron: Asymmetry
• Volume: 19
• Issue: 12
• Links: http://dx.doi.org/10.1016/j.tetasy.2008.05.024
• Document type: Journal article
• Publisher: Elsevier
• Topic: Organic Chemistry
• Status: Published
• ISBN/ISSN/Other: ISSN: 0957-4166