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Chlorhexidine for prevention of neonatal colonization with group B streptococci. III. Effect of vaginal washing with chlorhexidine before rupture of the membranes

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Author

Summary, in English

A single vaginal washing with 2 g/l of chlorhexidine was performed before rupture of the membranes in 19 parturients who were urogenital carriers of group B streptococci (GBS). Two (11%) of the infants became colonized immediately after birth, in contrast to 16 of 41 (39%) infants to controls (P = 0.02). A significant reduction of GBS colonization of the ear (P = 0.02) and umbilicus (P = 0.01) was noted. Taken together, 2 of 57 (4%) cultures obtained at birth were positive in the chlorhexidine group, in contrast to 30 of 123 (24%) among the controls (P less than 0.01). These findings raise hope for the design of a simple washing procedure which might prevent serious infections in the early neonatal period with GBS but also with other chlorhexidine-sensitive organisms.

Publishing year

1985

Language

English

Pages

231-236

Publication/Series

European Journal of Obstetrics, Gynecology, and Reproductive Biology

Volume

19

Issue

4

Document type

Journal article

Publisher

Elsevier

Topic

  • Obstetrics, Gynecology and Reproductive Medicine

Keywords

  • neonatal colonization
  • group B streptococci
  • chlorhexidine

Status

Published

ISBN/ISSN/Other

  • ISSN: 0301-2115