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Non-invasive gas monitoring in newborn infants using diode laser absorption spectroscopy: A case study

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Author

Summary, in English

Non-invasive diode laser spectroscopy was, for the first time, used to assess gas content in the intestines and the lungs of a new-born, 4 kg, baby. Two gases, water vapor and oxygen, were studied with two low-power tunable diode lasers, illuminating the surface skin tissue and detecting the diffusely emerging light a few centimeters away. The light, having penetrated into the tissue, had experienced absorption by gas located in the lungs and in the intestines. Very distinct water vapor signals were obtained from the intestines while imprint from oxygen was lacking, as expected. Detectable, but minor, signals of water vapor were also obtained from the lungs, illuminating the armpit area and detecting below the collar bone. Water vapor signals were seen but again oxygen signals were lacking, now due to the difficulties of penetration of the oxygen probing light into the lungs of this full-term baby. Ultra-sound images were obtained both from the lungs and from the stomach of the baby. Based on dimensions and our experimental findings, we conclude, that for early pre-term babies, also oxygen should be detectable in the lungs, in addition to intestine and lung detection of water vapor. The present paper focuses on the studies of the intestines while the lung studies will be covered in a forthcoming paper.

Publishing year

2012

Language

English

Publication/Series

SPIE Conference Proceedings

Volume

8229

Document type

Conference paper

Publisher

SPIE

Topic

  • Anesthesiology and Intensive Care

Keywords

  • surfactant
  • gastrointestinal tract
  • NEC
  • colic
  • lungs
  • oxygen
  • water vapor
  • spectroscopy
  • Diode laser

Conference name

Conference on Optical Diagnostics and Sensing XII - Toward Point-of-Care Diagnostics/4th Meeting of the Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissues

Conference date

2012-01-21 - 2012-01-26

Status

Published

Research group

  • Anaesthesiology and Intensive Care Medicine

ISBN/ISSN/Other

  • ISSN: 0277-786X
  • ISSN: 1996-756X